| Year: | 2000 |
| Team: | Michigan State Spartans |
| Conference: | Big Ten Conference |
| Short Conf: | Big Ten |
| Record: | 5–6 |
| Conf Record: | 2–6 |
| Hc Year: | 1st |
| Oc Year: | 2nd |
| Dc Year: | 2nd |
| Stadium: | Spartan Stadium (c. 72,027 AstroTurf) |
The 2000 Michigan State Spartans football team represented Michigan State University in the 2000 NCAA Division I-A football season. The Spartans played their home games at Spartan Stadium in East Lansing, Michigan. This was the first year for head coach Bobby Williams, who took over the program after previous head coach Nick Saban had left to take the head coaching position at Louisiana State University.
See also: 2000 NCAA Division I-A football rankings.
The following players were selected in the 2001 NFL draft.
| Player | Round | Pick | Position | NFL Team |
|---|---|---|---|---|
| 7 | 202 | Cornerback | Arizona Cardinals | |
| 7 | 217 | Guard | New York Jets | |
| 7 | 239 | Outside Linebacker | New England Patriots | |