The 2000 Mexx Benelux Open was a women's tennis tournament played on outdoor clay courts in Antwerp, Belgium that was part of the Tier IV category of the 2000 WTA Tour. It was the seventh edition of the tournament and was held from 15 May until 21 May 2000. First-seeded Amanda Coetzer won the singles title and the accompanying $22,000 first-prize money.
See main article: 2000 Mexx Benelux Open – Singles. Amanda Coetzer defeated 
Cristina Torrens Valero, 4–6, 6–2, 6–3
See main article: 2000 Mexx Benelux Open – Doubles. 
Sabine Appelmans / Kim Clijsters defeated 
Jennifer Hopkins / Petra Rampre, 6–1, 6–1