| Prevseason: | 1999 |
| Nextseason: | 2001 |
| Liga Sudamericana de Básquetbol | |
| Season: | 2000 |
| Champions: |  Vasco da Gama |
| Runners Up: |  Atenas |
| Semifinalists: | Marathon Franca Welcome |
| Teams: | 16 |
| Dates: | 16 February – 17 April 2000 |
The 2000 Liga Sudamericana de Básquetbol, or 2000 FIBA South American League, was the fifth edition of the second-tier tournament for professional basketball clubs from South America. The tournament began on 16 February 2000, and finished on 17 April 2000. Brazilian team Vasco da Gama won their second title, defeating Argentine club Atenas in the Grand Finals.
Teams were split into four groups of four teams each, and played each other in a round-robin format. The top two teams from each group advanced to the final stage, a best-of-three direct playoff elimination in the quarterfinals and the semifinals, and a best-of-five elimination series in the Grand Finals, where the champion was decided.
| Country | Team | |
|---|---|---|
| | Atenas | |
| Boca Juniors | ||
| Independiente de General Pico | ||
 | UTEPSA | |
| | Marathon Franca | |
| Vasco Barueri | ||
| Vasco da Gama | ||
| Provincial Osorno | ||
| Universidad de Concepción | ||
 | Caimanes de Barranquilla | |
 | UTE | |
| Sol de América | ||
 | Universidad Alas Peruanas | |
| Cordón | ||
| Welcome | ||
 | Trotamundos de Carabobo |
Atenas Cordoba: Marcelo Milanesio, Leandro Palladino, Héctor Campana, Jason Osborne - Leonardo Gutierrez. Coach: Pablo Coleffi
Season MVP: Jose Vargas