| Team: | Hamilton Tiger-Cats |
| Year: | 2000 |
| Record: | 9–9–0–2 |
| Division Place: | 2nd, East |
| General Manager: | Neil Lumsden |
| Coach: | Ron Lancaster |
| Stadium: | Ivor Wynne Stadium |
| Playoffs: | Lost East Semi-Final |
| Mop: | Joe Montford |
| Moc: | Michael Philbrick |
| Mor: | Willie Fells |
| Uniform: | File:CFL HAM Jersey 1997.png |
| Shortnavlink: | Tiger-Cats seasons |
The 2000 Hamilton Tiger-Cats season was the 43rd season for the team in the Canadian Football League and their 51st overall. The Tiger-Cats finished in second place in the East Division with a 9–9–0–2 record in the first CFL season that awarded points to overtime losses. The Tiger-Cats failed to defend their Grey Cup title when they lost to the Winnipeg Blue Bombers in the East Semi-Final.
| Rd | Pick | Player | Position | School |
|---|---|---|---|---|
| 2 | 14 | WR | North Dakota | |
| 3 | 22 | G | Western Michigan | |
| 4 | 30 | OL | Utah | |
| 5 | 38 | SB | Queen's | |
| 6 | 46 | OL | California, PA | |
| Week | Date | Opponent | Score | Result | Record | |
|---|---|---|---|---|---|---|
| A | June 21 | vs. Winnipeg Blue Bombers | 27–27 | Tie | 0–0–1 | |
| B | June 27 | at Montreal Alouettes | 43–33 | Loss | 0–1–1 |
| Montreal Alouettes | 18 | 12 | 6 | 0 | 0 | 594 | 379 | 24 | |
| Hamilton Tiger-Cats | 18 | 9 | 9 | 0 | 2 | 470 | 446 | 20 | |
| Winnipeg Blue Bombers | 18 | 7 | 10 | 1 | 1 | 539 | 596 | 16 | |
| 18 | 7 | 10 | 1 | 0 | 390 | 562 | 15 |
| Week | Date | Opponent | Score | Result | Record | Streak | |
|---|---|---|---|---|---|---|---|
| 1 | July 7 | vs. BC Lions | 33–26 | Loss | 0–1 | L1 | |
| 2 | July 14 | at Edmonton Eskimos | 28–21 | Win | 1–1 | W1 | |
| 3 | July 21 | vs. Saskatchewan Roughriders | 40–34 | Win | 2–1 | W2 | |
| 4 | July 28 | at Toronto Argonauts | 23–17 | Win | 3–1 | W3 | |
| 5 | Aug 4 | vs. Edmonton Eskimos | 16–10 | Loss | 3–2 | L1 | |
| 6 | Aug 11 | at Saskatchewan Roughriders | 29–23 | Win | 4–2 | W1 | |
| 7 | Aug 18 | vs. Montreal Alouettes | 37–26 | Win | 5–2 | W2 | |
| 8 | Aug 25 | at Winnipeg Blue Bombers | 38–33 | Loss | 5–3 | L1 | |
| 9 | Sept 4 | vs. Toronto Argonauts | 42–12 | Win | 6–3 | W1 | |
| 10 | Sept 10 | at Montreal Alouettes | 15–9 | Win | 7–3 | W2 | |
| 11 | Sept 16 | at Calgary Stampeders | 41–38 | Loss | 7–4 | L1 | |
| 12 | Sept 23 | vs. Winnipeg Blue Bombers | 43–6 | Win | 8–4 | W1 | |
| 13 | Sept 30 | vs. Montreal Alouettes | 32–16 | Loss | 8–5 | L1 | |
| 14 | Oct 7 | at Toronto Argonauts | 29–12 | Loss | 8–6 | L2 | |
| 15 | Oct 13 | vs. Toronto Argonauts | 32–8 | Loss | 8–7 | L3 | |
| 16 | Oct 20 | at Winnipeg Blue Bombers | 27–24 | Loss | 8–8 | L4 | |
| 17 | Oct 28 | at BC Lions | 28–22 | Loss | 8–9 | L5 | |
| 18 | Nov 5 | vs. Calgary Stampeders | 24–22 | Win | 9–9 | W1 |