| Club: | Real Betis |
| Season: | 2000–01 |
| Chrtitle: | President |
| Chairman: | Manuel Ruiz de Lopera |
| Mgrtitle: | Head coach |
| Manager: | Fernando Vázquez (until 19 March) Luis del Sol (from 25 March)[1] |
| Stadium: | Estadio Manuel Ruiz de Lopera |
| League: | Segunda División |
| League Result: | 2nd |
| Cup1: | Copa del Rey |
| Cup1 Result: | Round of 64[2] |
| League Topscorer: | Gabriel Amato (16) |
| Season Topscorer: | Gabriel Amato (16) |
| Prevseason: | 1999–2000 |
| Nextseason: | 2001–02 |
The 2000–01 season was the 94th season in the existence of Real Betis and the club's first season back in the second division of Spanish football since 1994.
See main article: 2000–01 Segunda División.
See main article: 2000–01 Copa del Rey.
| Player | La Liga | Copa del Rey | Total | ||||
|---|---|---|---|---|---|---|---|
| 1 | FW | 9 | 16 | 0 | 16 | ||
| 2 | FW | 19 | 11 | 0 | 11 | ||
| 3 | FW | 20 | 4 | 1 | 5 | ||
| 4 | FW | 27 | 3 | 0 | 3 | ||
| FW | 22 | 3 | 0 | 3 | |||
| Total | 49 | 1 | 50 | ||||