| Mode: | Women's basketball |
| Year: | 2000–01 |
| Prev Year: | 1999–2000 |
| Next Year: | 2001–02 |
| Team: | Purdue Boilermakers |
| Conference: | Big Ten Conference |
| Short Conf: | Big Ten |
| Coachrank: | 2 |
| Aprank: | 9 |
| Record: | 31–7 |
| Conf Record: | 14–2 |
| Hc Year: | 2nd |
| Champion: | Big Ten regular season champions |
| Tourney Result: | Runner-up |
The 2000–01 Purdue Boilermakers women's basketball team represented Purdue University as a member of the Big Ten Conference during the 2000–01 NCAA Division I women's basketball season. Led by second-year head coach Kristy Curry, the Boilermakers played their home games at Mackey Arena in West Lafayette, Indiana. Purdue finished the regular season with a 14–2 record in Big Ten play to capture the regular season title. They were upset by Iowa in the Big Ten tournament, but received a bid to the NCAA tournament as No. 3 seed in the Mideast region. The Boilermakers beat UC Santa Barbara, LSU, Texas Tech, and Xavier to reach their second Final Four in three seasons. They defeated SW Missouri State in the National semifinals. In the National championship game, Purdue lost to Notre Dame by just two points, 68–66.
|-!colspan=12 style=""|Regular season
|-!colspan=12 style=""|Big Ten tournament|-!colspan=12 style=""|NCAA tournamentSource[1]
See main article: 2000–01 NCAA Division I women's basketball rankings.