| Mode: | Basketball |
| Year: | 2000–01 |
| Prev Year: | 1999–2000 |
| Next Year: | 2001–02 |
| Team: | Ole Miss Rebels |
| Conference: | Southeastern Conference |
| Short Conf: | SEC |
| Coachrank: | 14 |
| Aprank: | 14 |
| Record: | 27–8 |
| Conf Record: | 11–5 |
| Hc Year: | 3rd |
| Asst Coach1: | Marc Dukes |
| Ac1 Year: | 3rd |
| Asst Coach2: | Eric Bozeman |
| Ac2 Year: | 3rd |
| Ac3 Year: | 3rd |
| Champion: | SEC West champions |
| Tourney Result: | Sweet Sixteen |
The 2000–01 Ole Miss Rebels men's basketball team represented the University of Mississippi in the 2000–01 NCAA Division I men's basketball season. The Rebels were led by third-year head coach, Rod Barnes. The Rebels played their home games at Tad Smith Coliseum in Oxford, Mississippi as members of the Southeastern Conference. This season marked the sixth NCAA Tournament appearance in school history.
|-!colspan=6 style=|Non-conference regular season|-!colspan=6 style=|SEC regular season|-!colspan=12 style=| SEC tournament|-!colspan=12 style=| NCAA tournament
Source: [2]