| Competition: | NSW Premier League |
| Season: | 2000–01 |
| Winners: | Bonnyrigg White Eagles |
| Premiers: | Blacktown City FC |
| Matches: | 94 |
| Total Goals: | 333 |
| Prevseason: | 2000 |
| Nextseason: | 2001–02 |
The 2000–01 NSW Premier League season was the inaugural season of the NSW Premier League. The competition replaced the NSW Super League as the top-tier competition in New South Wales. The season moved away from a winter league to a summer league to align with the then premier national competition, the National Soccer League. The second-tier competition became the NSW Winter Super League.
The competition began on Friday, 3 November 2000 at St George Stadium for the Round 1 fixture between St George Saints and Canterbury-Marrickville. The competition concluded with the grand final being played on Sunday, 8 April 2001 at Marconi Stadium, with Bonnyrigg White Eagles FC taking out the title by defeating Premiers Blacktown City FC 3–1.
| Club | Ground | Capacity | |
|---|---|---|---|
| A.P.I.A. Leichhardt Tigers | Lambert Park | 7,000 | |
| Belconnen Blue Devils | Belconnen Soccer Centre | 2,000 | |
| Blacktown City Demons FC | Fairfax Community Stadium | 7,500 | |
| Bonnyrigg White Eagles FC | Bonnyrigg Sports Club | 10,000 | |
| Canterbury-Marrickville Olympic | The Crest Reserve | ||
| Central Coast Coasties | Pluim Park | ||
| Parramatta Eagles | Melita Stadium | 10,000 | |
| Penrith Panthers | CUA Stadium | 21,000 | |
| St George Saints | St George Stadium | 15,000 | |
| Sutherland Sharks | Seymour Shaw Park | 5,000 |