| Mode: | Women's Basketball |
| Year: | 2000-01 |
| Prev Year: | 1999-2000 |
| Next Year: | 2001-02 |
| Team: | Connecticut Huskies |
| Short Conf: | Big East |
| Coachrank: | 3 |
| Aprank: | 1 |
| Record: | 32–3 |
| Conf Record: | 15–1 |
| Hc Year: | 16th |
| Champion: | Big East tournament champions Big East regular season co-champions |
| Tourney Result: | Final Four |
The 2000–01 Connecticut Huskies women's basketball team represented the University of Connecticut during the 2000–01 NCAA Division I basketball season. Coached by Geno Auriemma, the Huskies played their home games at the Hartford Civic Center in Hartford, Connecticut, and on campus at the Harry A. Gampel Pavilion in Storrs, Connecticut, and are a member of the Big East Conference.
The Huskies opened the season with a No. 1 ranking in both major polls, a position they held for over half the season before a road loss at No. 3 Notre Dame. UConn would regain the top spot after winning the Big East tournament. The team received an automatic bid to the NCAA tournament as the No. 1 seed in the East region. The Huskies overwhelmed Long Island and Colorado State to reach the Sweet Sixteen. UConn won the East regional, played in Pittsburgh, with double-digit wins over No. 4 seed NC State and No. 3 seed Louisiana Tech. In the Final Four, the Huskies were beaten by No. 2-ranked and fellow Big East foe, Notre Dame, 90–75. The loss lit a fire within the program as the team would go on to become three-peat National champions from 2002 to 2004.
|-!colspan=9 style=| Regular season
|-!colspan=9 style=| Big East tournament|-!colspan=9 style=| NCAA tournament[1]
See main article: 2000–01 NCAA Division I women's basketball rankings.