2-phosphosulfolactate phosphatase explained

2-phosphosulfolactate phosphatase
Ec Number:	3.1.3.71
Go Code:	0050532

The enzyme 2-phosphosulfolactate phosphatase^[1] (EC 3.1.3.71) catalyzes the reaction

(2R)-2-phospho-3-sulfolactate + H₂O

\rightleftharpoons (2R)-3-sulfolactate + phosphate

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name (R)-2-phospho-3-sulfolactate phosphohydrolase. Other names in common use include (2R)-phosphosulfolactate phosphohydrolase, and ComB phosphatase.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code .

Notes and References

1. Graham DE, Graupner M, Xu H, White RH . 2001 . Identification of coenzyme M biosynthetic 2-phosphosulfolactate phosphatase. A member of a new class of Mg²⁺-dependent acid phosphatases . Eur. J. Biochem. . 268 . 5176 - 88 . 11589710 . 10.1046/j.0014-2956.2001.02451.x . 19 . free .