2-Methylindole Explained

Methylketol or 2-methylindole is a mildly toxic and slightly flammable organic compound which occurs as a white solid which turns brown over time.^{[1] [2]} It has chemical formula.^[3]

Methylketol is used as an intermediate for synthesizing dyes,^[4] pigments,^[5] optical brighteners, and pharmaceuticals.^[6]

See also

• Indole
• Methyl
• 1-Methylindole
• 5-Methylindole
• 7-Methylindole
• Skatole (3-methylindole)

References

1. Brown . Daniel R. . Clark . Bryan W. . Garner . Lindsey V. T. . Di Giulio . Richard T. . June 2015 . Zebrafish cardiotoxicity: the effects of CYP1A inhibition and AHR2 knockdown following exposure to weak aryl hydrocarbon receptor agonists . Environmental Science and Pollution Research International . 22 . 11 . 8329–8338 . 10.1007/s11356-014-3969-2 . 1614-7499 . 4442063 . 25532870. 2015ESPR...22.8329B .
2. Brown . D. R. . Clark . B. W. . Garner . L. V. T. . Di Giulio . R. T. . October 2016 . Embryonic cardiotoxicity of weak aryl hydrocarbon receptor agonists and CYP1A inhibitor fluoranthene in the Atlantic killifish (Fundulus heteroclitus) . Comparative Biochemistry and Physiology. Toxicology & Pharmacology . 188 . 45–51 . 10.1016/j.cbpc.2016.05.005 . 1532-0456 . 27211013.
3. Parker . Amie . Lamata . Pilar . Viguri . Fernando . Rodríguez . Ricardo . López . José A. . Lahoz . Fernando J. . García-Orduña . Pilar . Carmona . Daniel . 2020-10-12 . Half-sandwich complexes of osmium containing guanidine-derived ligands . Dalton Transactions . 49 . 39 . 13601–13617 . 10.1039/d0dt02713h . 1477-9234 . 32975256. 221913494 . 10261/233133 . free .
4. Casas-Catalán . María José . Doménech-Carbó . María Teresa . May 2005 . Identification of natural dyes used in works of art by pyrolysis-gas chromatography/mass spectrometry combined with in situ trimethylsilylation . Analytical and Bioanalytical Chemistry . 382 . 2 . 259–268 . 10.1007/s00216-005-3064-0 . 1618-2642 . 15782338. 44407380 .
5. Shaki . Hanieh . Gharanjig . Kamaladin . Khosravi . Alireza . July 2015 . Synthesis and investigation of antimicrobial activity and spectrophotometric and dyeing properties of some novel azo disperse dyes based on naphthalimides . Biotechnology Progress . 31 . 4 . 1086–1095 . 10.1002/btpr.2107 . 1520-6033 . 25967675. 25349059 .
6. Ozcan-Sezer . Senem . Ince . Elif . Akdemir . Atilla . Ceylan . Özlem Öztürk . Suzen . Sibel . Gurer-Orhan . Hande . May 2019 . Aromatase inhibition by 2-methyl indole hydrazone derivatives evaluated via molecular docking and in vitro activity studies . Xenobiotica; the Fate of Foreign Compounds in Biological Systems . 49 . 5 . 549–556 . 10.1080/00498254.2018.1482029 . 1366-5928 . 29804490. 44062839 .