| 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase | |
| Ec Number: | 1.1.1.127 |
| Cas Number: | 37250-56-9 |
| Go Code: | 0047001 |
In enzymology, a 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase is an enzyme that catalyzes the chemical reaction
2-dehydro-3-deoxy-D-gluconate + NAD+
\rightleftharpoons
Thus, the two substrates of this enzyme are 2-dehydro-3-deoxy-D-gluconate and NAD+, whereas its 3 products are (4S)-4,6-dihydroxy-2,5-dioxohexanoate, NADH, and H+.
This enzyme participates in pentose and glucuronate interconversions.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-dehydro-3-deoxy-D-gluconate:NAD+ 5-oxidoreductase. Other names in common use include 2-keto-3-deoxygluconate 5-dehydrogenase, 2-keto-3-deoxy-D-gluconate dehydrogenase, 2-keto-3-deoxygluconate (nicotinamide adenine dinucleotide, (phosphate)) dehydrogenase, 2-keto-3-deoxy-D-gluconate (3-deoxy-D-glycero-2,5-hexodiulosonic, and acid) dehydrogenase.