2-Phenyl-2-propanol explained

2-Phenyl-2-propanol is a chemical compound that belongs to the alcohol group. It is a derivative of cumene.

Synthesis

2-Phenyl-2-propanol can be synthesized through Grignard reaction between phenylmagnesium bromide and acetone.[1]

Properties

2-Phenyl-2-propanol is a white to pale-yellow, odorless solid which is combustible yet difficult to ignite and barely dissolves in water.

Applications

2-Phenyl-2-propanol can either be applied in organic syntheses, or be reactants or intermediates in agrochemical, medical, and dyestuff fields.

2-Phenyl-2-propanol is the main metabolite of cumene, and therefore 2-phenyl-2-propanol can serve as a biomarker of cumene.

Hazards

According to a report of Federal Institute for Risk Assessment in 2008, there is strong evidence that 2-phenyl-2-propanol may lead to allergic reactions for humans.[2]

Notes and References

  1. Albany College of Pharmacy and Health Sciences: Preparation of 2-Phenyl-2-propanol (Grignard Reaction), retrieved 16 April 2017.
  2. BfR: Verbraucher sollten Plastik-Clogs mit starkem Geruch meiden, Stellungnahme Nr. 047/2008 des BfR of 5 November 2008.