2-Methyl-2-propyl-1,3-propanediol explained
2-Methyl-2-propyl-1,3-propanediol (MPP) is a simple alkyl diol which has sedative, anticonvulsant and muscle relaxant effects.
Precursor/metabolite
It is both a synthetic precursor to, and an active metabolite of tranquilizers and other derivatives:[1] [2] [3] [4]
- Carisoprodol
- Lorbamate
- Meprobamate
- Tolboxane
- Tybamate
See also
Notes and References
- Wang G, Lu Q . A nitrate ester of sedative alkyl alcohol improves muscle function and structure in a murine model of Duchenne muscular dystrophy . Molecular Pharmaceutics . 10 . 10 . 3862–70 . October 2013 . 23924275 . 10.1021/mp400310r .
- Yale HL, Pribyl EJ, Braker W, Bergeim FH, Lott WA . Muscle-relaxing Compounds Similar to 3-(o-Toloxy)-1, 2-propanediol. 1 I. Aromatic Ethers of Polyhydroxy Alcohols and Related Compounds. . Journal of the American Chemical Society . August 1950 . 72 . 8 . 3710–6 . 10.1021/ja01164a108 .
- Kato K, Tsukamoto K . 2-(2-Alkenyl)-1,3-propanediols and preparation of 2,2-disubstituted-1,3-propanediols . 1997 . JP . 09031000 .
- Kaithal A, Hölscher M, Leitner W . Catalytic Hydrogenation of Cyclic Carbonates using Manganese Complexes . Angewandte Chemie International Edition in English. 57 . 41 . 13449–13453 . October 2018 . 30134081 . 6221167 . 10.1002/anie.201808676 .
