2-MCPD explained

2-MCPD (2-chloropropane-1,3-diol) is an organic chemical compound with the formula . It is a colorless liquid. The compound has attracted notoreity as a food contaminant. Together with the 3-MCPD, it is one of two chloropropanols food contaminants.^[1] It is suspected to be carcinogenic in humans.^[2]

2-MCPD, together with its isomer 3-MCPD, is thought to be produced when fat-containing foods are treated at high temperatures with hydrochloric acid. Such treatments are sometimes used to accelerate protein hydrolysis, making food more digestable. In such a treatment chloride is thought to react with the glycerol backbone of lipids to produce 2- and 3-MCPD.

Further reading

• 10.5740/jaoacint.19-0026 . 2-Monochloropropanediol (2-MCPD), 3-Monochloropropanediol (3-MCPD), and Glycidol in Infant and Adult/Pediatric Nutritional Formula: Single-Laboratory Validation, First Action 2018.12 . 2019 . Kuhlmann . Jan . Journal of AOAC International . 102 . 4 . 1205–1220 . 30992094 .
• 25354796 . 2015 . Buhrke . T. . Frenzel . F. . Kuhlmann . J. . Lampen . A. . 2-Chloro-1,3-propanediol (2-MCPD) and its fatty acid esters: Cytotoxicity, metabolism, and transport by human intestinal Caco-2 cells . Archives of Toxicology . 89 . 12 . 2243–2251 . 10.1007/s00204-014-1395-3 .

External links

• Chloropropanols (WHO Food Additive Series 32)

Notes and References

1. 10.1021/es903383a. 20163179. Identifying New Persistent and Bioaccumulative Organics Among Chemicals in Commerce. Environmental Science & Technology. 44. 7. 2277–2285. 2010. Howard. Philip H.. Muir. Derek C. G.. 2010EnST...44.2277H. free.
2. 10.2903/j.efsa.2016.4426 . Risks for human health related to the presence of 3- and 2-monochloropropanediol (MCPD), and their fatty acid esters, and glycidyl fatty acid esters in food . EFSA Journal . 2016 . 14 . 5 . 2164/7793 . free .