2-Ketoarginine methyltransferase explained

2-Ketoarginine methyltransferase
Ec Number:	2.1.1.243

2-Ketoarginine methyltransferase (mrsA (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:5-carbamimidamido-2-oxopentanoate S-methyltransferase.^[1] This enzyme catalyses the following chemical reaction

\rightleftharpoons S-adenosyl-L-homocysteine + 5-guanidino-3-methyl-2-oxopentanoate

The enzyme is involved in production of the rare amino acid 3-methylarginine.

Notes and References

1. Braun SD, Hofmann J, Wensing A, Ullrich MS, Weingart H, Völksch B, Spiteller D . Identification of the biosynthetic gene cluster for 3-methylarginine, a toxin produced by Pseudomonas syringae pv. syringae 22d/93 . Applied and Environmental Microbiology . 76 . 8 . 2500–8 . April 2010 . 20190091 . 2849186 . 10.1128/aem.00666-09 .