2-Formylbenzoate dehydrogenase explained

2-Formylbenzoate dehydrogenase
Ec Number:	1.2.1.78

2-Formylbenzoate dehydrogenase (2-carboxybenzaldehyde dehydrogenase, 2CBAL dehydrogenase, PhdK) is an enzyme with systematic name 2-formylbenzoate:NAD⁺ oxidoreductase.^{[1] [2]} This enzyme catalyses the following chemical reaction

2-formylbenzoate + NAD⁺ + H₂O

\rightleftharpoons o-phthalic acid + NADH + H⁺

The enzyme is involved in phenanthrene degradation.

Notes and References

1. Iwabuchi T, Harayama S . Biochemical and genetic characterization of 2-carboxybenzaldehyde dehydrogenase, an enzyme involved in phenanthrene degradation by Nocardioides sp. strain KP7 . Journal of Bacteriology . 179 . 20 . 6488–94 . October 1997 . 9335300 . 179567 .
2. Isolation and some properties of NAD-linked 2-carboxybenzaldehyde dehydrogenase in Alcaligenes faecalis AFK 2 grown on phenanthrene . Kiyohara H, Nagao K, Yano K . J. Gen. Appl. Microbiol. . 1981 . 27 . 443–455 . 10.2323/jgam.27.443. free .