2-Chloromethylpyridine Explained

2-Chloromethylpyridine is an organohalide that consists of a pyridine core bearing a chloromethyl group. It is one of three isomeric chloromethylpyridines, along with 3- and 4-chloromethylpyridine. It is an alkylating agent. 2-Chloromethylpyridine is a precursor to pyridine-containing ligands.[1] [2]

Safety

2-Chloromethylpyridine is an analogue of nitrogen mustards, and has been investigated for its mutagenicity.

Notes and References

  1. 10.1021/acs.organomet.0c00717. Cationic PCP and PCN NHC Core Pincer-Type Mn(I) Complexes: From Synthesis to Catalysis. 2021. Buhaibeh. Ruqaya. Duhayon. Carine. Valyaev. Dmitry A.. Sortais. Jean-Baptiste. Canac. Yves. Organometallics. 40. 2. 231–241. 234156476 .
  2. 10.1021/ic00062a047. Chelating Properties of 2-((Diphenylphosphino)methyl)pyridine N,P-dioxide and 2,6-Bis((diphenylphosphino)methyl)pyridine N,P,P-trioxide Toward f-Element Ions. 1993. Rapko. B. M.. Duesler. E. N.. Smith. P. H.. Paine. R. T.. Ryan. R. R.. Inorganic Chemistry. 32. 10. 2164–2174.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "2-Chloromethylpyridine".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.