2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase explained

2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase
Ec Number:	5.3.3.18

2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase (paaG (gene), 1,2-epoxyphenylacetyl-CoA isomerase) is an enzyme with systematic name 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase.^{[1] [2]} This enzyme catalyses the following chemical reaction

2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA

\rightleftharpoons 2-oxepin-2(3H)-ylideneacetyl-CoA

The enzyme catalyses the reversible isomerization of 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA.

Notes and References

1. Ismail W, El-Said Mohamed M, Wanner BL, Datsenko KA, Eisenreich W, Rohdich F, Bacher A, Fuchs G . Functional genomics by NMR spectroscopy. Phenylacetate catabolism in Escherichia coli . European Journal of Biochemistry . 270 . 14 . 3047–54 . July 2003 . 12846838 . 10.1046/j.1432-1033.2003.03683.x . free .
2. Teufel R, Mascaraque V, Ismail W, Voss M, Perera J, Eisenreich W, Haehnel W, Fuchs G . Bacterial phenylalanine and phenylacetate catabolic pathway revealed . Proceedings of the National Academy of Sciences of the United States of America . 107 . 32 . 14390–5 . August 2010 . 20660314 . 2922514 . 10.1073/pnas.1005399107 . 2010PNAS..10714390T . free .