2,4-Dichloroamphetamine Explained

Class:Psychostimulant
Serotonergic neurotoxin; Monoamine oxidase inhibitor
Cas Number:32560-77-3
Pubchem:3041175
Chemspiderid:2304480
Synonyms:2,4-DCA
Iupac Name:1-(2,4-dichlorophenyl)propan-2-amine
C:9
H:11
Cl:2
N:1
Smiles:CC(CC1=C(C=C(C=C1)Cl)Cl)N
Stdinchi:1S/C9H11Cl2N/c1-6(12)4-7-2-3-8(10)5-9(7)11/h2-3,5-6H,4,12H2,1H3
Stdinchikey:WFXOKSCQUWGEEH-UHFFFAOYSA-N

2,4-Dichloroamphetamine (2,4-DCA) is a psychostimulant of the amphetamine family and a potent serotonergic neurotoxin related to para-chloroamphetamine (PCA; 4-chloroamphetamine).[1] [2] It is also a potent monoamine oxidase inhibitor.[3]

See also

Notes and References

  1. Book: Biel JH, Bopp BA . Amphetamines: Structure-Activity Relationships. Iversen L, Snyder SH, Iversen SD . Stimulants . Springer US . Boston, MA . 1978 . 978-1-4757-0512-6 . 10.1007/978-1-4757-0510-2_1 . 1–39.
  2. Fuller RW, Snoddy HD, Roush BW, Molloy BB . Further structure-activity studies on the lowering of brain 5-hydroxyindoles by 4-chloramphetamine . Neuropharmacology . 12 . 1 . 33–42 . January 1973 . 4687274 . 10.1016/0028-3908(73)90129-9 . Elsevier BV .
  3. Conde S, Madroñero R, Fernández-Tomé MP, del Río J . Effects of thiophene analogues of chloroamphetamines on central serotonergic mechanisms . Journal of Medicinal Chemistry . 21 . 9 . 978–981 . September 1978 . 722762 . 10.1021/jm00207a024 . American Chemical Society (ACS) .