2,5-Dimethoxy-4-isopropylamphetamine explained
2,5-Dimethoxy-4-isopropylamphetamine (also known as DOiP and DOiPr) is a psychedelic drug of the phenethylamine and amphetamine chemical classes.[1] [2] [3] It was first synthesized by Alexander Shulgin, and was described in his book PiHKAL (Phenethylamines i Have Known And Loved). Shulgin described DOiPR as being at least an order of magnitude weaker than DOPr, with doses of 20–30 mg required to produce valid changes in mental state.[4] Very little data exists about the pharmacological properties, metabolism, and toxicity of DOiPR.
See also
Notes and References
- Book: Interaction of phenylisopropylamines with central 5-HT2 receptors. Analysis by quantitative structure-activity relationships.. Probing Bioactive Mechanisms . Glennon RA, Seggel MR . ACS Symposium Series . November 1989 . 413 . 264–280 . 10.1021/bk-1989-0413.ch018. 978-0-8412-1702-7.
- Bryan Roth . Seggel MR, Yousif MY, Lyon RA, Titeler M, Roth BL, Suba EA, Glennon RA . A structure-affinity study of the binding of 4-substituted analogues of 1-(2,5-dimethoxyphenyl)-2-aminopropane at 5-HT2 serotonin receptors . Journal of Medicinal Chemistry . 33 . 3 . 1032–6 . March 1990 . 2308135 . 10.1021/jm00165a023 .
- Aldous FA, Barrass BC, Brewster K, Buxton DA, Green DM, Pinder RM, Rich P, Skeels M, Tutt KJ . 6 . Structure-activity relationships in psychotomimetic phenylalkylamines . Journal of Medicinal Chemistry . 17 . 10 . 1100–11 . October 1974 . 4418757 . 10.1021/jm00256a016 .
- Web site: PiHKAL: A Chemical Love Story #71 DOPR . Transform Press . September 1991 . 27 June 2015 . Shulgin A, Shulgin A . 978.
