2,4-dienoyl-CoA reductase 1 explained
2,4-dienoyl-CoA reductase 1 is a protein that in humans is encoded by the DECR1 gene.[1]
Function
This gene encodes an accessory enzyme which participates in the beta-oxidation and metabolism of unsaturated fatty enoyl-CoA esters.
See also
Further reading
- Alphey MS, Yu W, Byres E, Li D, Hunter WN . Structure and reactivity of human mitochondrial 2,4-dienoyl-CoA reductase: enzyme-ligand interactions in a distinctive short-chain reductase active site . J. Biol. Chem. . 280 . 4 . 3068–77 . 2005 . 15531764 . 10.1074/jbc.M411069200 . free .
- Yu W, Chu X, Chen G, Li D . Studies of human mitochondrial 2,4-dienoyl-CoA reductase . Arch. Biochem. Biophys. . 434 . 1 . 195–200 . 2005 . 15629123 . 10.1016/j.abb.2004.10.018 .
- Rosenzweig SD . Inflammatory manifestations in chronic granulomatous disease (CGD) . J. Clin. Immunol. . 28 . S67–72 . 2008 . Suppl 1 . 18193341 . 10.1007/s10875-007-9160-5 . 5965278 .
- Kardon T, Senesi S, Marcolongo P, Legeza B, Bánhegyi G, Mandl J, Fulceri R, Benedetti A . Maintenance of luminal NADPH in the endoplasmic reticulum promotes the survival of human neutrophil granulocytes . FEBS Lett. . 582 . 13 . 1809–15 . 2008 . 18472006 . 10.1016/j.febslet.2008.04.045 . 41166916 . free .
- Mizuta I, Tsunoda T, Satake W, Nakabayashi Y, Watanabe M, Takeda A, Hasegawa K, Nakashima K, Yamamoto M, Hattori N, Murata M, Toda T . Calbindin 1, fibroblast growth factor 20, and alpha-synuclein in sporadic Parkinson's disease . Hum. Genet. . 124 . 1 . 89–94 . 2008 . 18568448 . 10.1007/s00439-008-0525-5 . 20604147 .
- Moe KT, Woon FP, De Silva DA, Wong P, Koh TH, Kingwell B, Chin-Dusting J, Wong MC . Association of acute ischemic stroke with the MTHFR C677T polymorphism but not with NOS3 gene polymorphisms in a Singapore population . Eur. J. Neurol. . 15 . 12 . 1309–14 . 2008 . 19049547 . 10.1111/j.1468-1331.2008.02308.x . 10457617 .
- Hosgood HD, Zhang L, Shen M, Berndt SI, Vermeulen R, Li G, Yin S, Yeager M, Yuenger J, Rothman N, Chanock S, Smith M, Lan Q . Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity . Occup Environ Med . 66 . 12 . 848–53 . 2009 . 19773279 . 2928224 . 10.1136/oem.2008.044024 .
- Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR . Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score . Mol. Med. . 16 . 7–8 . 247–53 . 2010 . 20379614 . 2896464 . 10.2119/molmed.2009.00159 .
- Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ . Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression . PLOS ONE . 5 . 9 . e12862 . 2010 . 20877624 . 2943476 . 10.1371/journal.pone.0012862 . 2010PLoSO...512862H . free .
Notes and References
- Web site: Entrez Gene: 2,4-dienoyl-CoA reductase 1. 2017-09-12.
