2,4-Xylidine Explained

2,4-Xylidine is an organic compound with the formula C6H3(CH3)2NH2. It is one of several isomeric xylidines. It is a colorless viscous liquid. Commercially significant derivatives include the veterinary drug cymiazole and the colorant Pigment Yellow 81.[1]

Genotoxic and teratogenic, 2,4xylidine is an industrial pollutant.[2] In addition, it is a degradant of the pesticide amitraz at very acidic pH values (<3).[3]

It is prepared by nitration of m-xylene followed by hydrogenation.

References

  1. Encyclopedia: M.. Meyer. Xylidines. Ullmann's Encyclopedia of Industrial Chemistry. Wiley-VCH. Weinheim. 2012. 10.1002/14356007.a28_455. 978-3527306732.
  2. 17090125 . 2006 . Brimecombe . R. D. . Electrochemical monitoring of the biodegradation of 2,4-dimethylaniline . Journal of Agricultural and Food Chemistry . 54 . 23 . 8799–8803 . Fogel . R. . Limson . J. L. . 10.1021/jf061951k.
  3. 10.1016/s0039-9140(98)00237-9 . 18967458. Kinetics and mechanism of amitraz hydrolysis in aqueous media by HPLC and GC-MS. Talanta. 48. 189–199. 1999. Corta . E. W.. Bakkali . A.. Berrueta . L. A.. Gallo . B.. Vicente . F.. 1 .