2,3-diketo-5-methylthiopentyl-1-phosphate enolase explained

2,3-diketo-5-methylthiopentyl-1-phosphate enolase
Ec Number:	5.3.2.5

2,3-diketo-5-methylthiopentyl-1-phosphate enolase (DK-MTP-1-P enolase, MtnW, YkrW, RuBisCO-like protein, RLP) is an enzyme with systematic name 2,3-diketo-5-methylthiopentyl-1-phosphate keto-enol-isomerase.^{[1] [2]} This enzyme catalyses the following chemical reaction

5-(methylthio)-2,3-dioxopentyl phosphate

\rightleftharpoons 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate

The enzyme participates in the methionine salvage pathway in Bacillus subtilis.

Notes and References

1. Myers RW, Wray JW, Fish S, Abeles RH . Purification and characterization of an enzyme involved in oxidative carbon-carbon bond cleavage reactions in the methionine salvage pathway of Klebsiella pneumoniae . The Journal of Biological Chemistry . 268 . 33 . 24785–91 . November 1993 . 8227039 .
2. Ashida H, Saito Y, Kojima C, Kobayashi K, Ogasawara N, Yokota A . A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO . Science . 302 . 5643 . 286–90 . October 2003 . 14551435 . 10.1126/science.1086997 .