2,2'-Dipyridyldisulfide Explained
2,2′-Dipyridyldisulfide, sometimes known as DPS, is used for preparing thiols[1] [2] and activating carboxylic acid for coupling reactions, as in the following reaction:[3]
Uses
It is also used in molecular biology as an oxidising agent, for example to oxidise free thiols to form disulfide bonds in proteins.
Notes and References
- Futaki S. and Kitagawa K. . Peptide-Unit Assembling Using Disulfide Cross-Linking - a New Approach for Construction of Protein Models . 1994 . . 35 . 8 . 1267–1270 . 10.1016/0040-4039(94)88040-9.
- . Special Reagents for Thiol Groups . 4 . 3 . 33–46.
- . Thalmann A., Oertle K. and Gerlach H . Ricinelaidic acid lactone. 1985 . 7 . 470 . 10.15227/orgsyn.063.0192.