| Women's World Open 1999 | |
| Number: | 16 |
| Series: | WISPA World Squash Championship |
| Location: |  Seattle, United States |
| Dates: | October 16–24, 1999 |
| Category: | World Open |
| Prize Money: | $80,000 |
| Champion: | Cassie Campion |
| Runner-Up: |  Michelle Martin |
| Semi-Finalists: |  Leilani JoyceNatalie Grainger |
| Next: | 2000 |
The 1999 Women's World Open Squash Championship was the women's edition of the 1999 World Open, which serves as the individual world championship for squash players. The event took place in Seattle in the United States from 16 October until 24 October 1999. Cassie Campion won the World Open title, defeating Michelle Martin in the final.[1]
Cassie Campion was formerly Cassie Jackman.
Sarah Fitzgerald was unable to defend her title due to injury.