| Sport: | football |
| Year: | 1999 |
| Team: | Rice Owls |
| Conference: | Western Athletic Conference |
| Short Conf: | WAC |
| Record: | 5 - 6 |
| Conf Record: | 4 - 3 |
| Hc Year: | 6th |
| Oc Year: | 6th |
| Def Coach: | Roger Hinshaw |
| Dc Year: | 2nd as DC, 6th overall |
The 1999 Rice Owls football team represented Rice University in the 1999 NCAA Division I-A college football season. The Owls, led by head coach Ken Hatfield, played their home games at Rice Stadium in Houston, Texas.