| Year: | 1999 |
| Team: | Ole Miss Rebels |
| Sport: | football |
| Conference: | Southeastern Conference |
| Division: | Western Division |
| Short Conf: | SEC |
| Coachrank: | 22 |
| Aprank: | 22 |
| Record: | 8–4 |
| Conf Record: | 4–4 |
| Head Coach: | David Cutcliffe |
| Hc Year: | 1st |
| Def Coach: | Art Kaufman |
| Dc Year: | 5th |
| Stadium: | Vaught–Hemingway Stadium |
| Champion: | Independence Bowl champion |
| Bowl: | Independence Bowl |
| Bowl Result: | W 27–25 vs. Oklahoma |
The 1999 Ole Miss Rebels football team represented the University of Mississippi during the 1999 NCAA Division I-A football season. They participated as members of the Southeastern Conference in the West Division. Coached by David Cutcliffe, the Rebels played their home games at Vaught–Hemingway Stadium in Oxford, Mississippi.