| Year: | 1999 |
| Team: | Missouri Tigers |
| Sport: | football |
| Conference: | Big 12 Conference |
| Division: | North Division |
| Short Conf: | Big 12 |
| Record: | 4–7 |
| Conf Record: | 1–7 |
| Head Coach: | Larry Smith |
| Hc Year: | 6th |
| Off Coach: | Jerry Berndt |
| Oc Year: | 6th |
| Def Coach: | Moe Ankney |
| Dc Year: | 6th |
| Stadium: | Faurot Field |
The 1999 Missouri Tigers football team represented the University of Missouri during the 1999 NCAA Division I-A football season. They played their home games at Faurot Field in Columbia, Missouri. They were members of the Big 12 Conference in the North Division. The team was coached by head coach Larry Smith.
| Name | Position | Seasons at Missouri | Alma mater |
|---|---|---|---|
| Larry Smith | Head coach | 6 | Bowling Green (1961) |
| Jerry Berndt | Offensive coordinator & quarterbacks | 6 | Wisconsin–Superior (1960) |
| Corbyn Smith | Offensive tackle, tight end & Special teams coordinator | 2 | Iowa (1995) |
| David Mitchell | Running backs | 3 | Arkansas State |
| Andy Hill | Wide receivers | 4 | Missouri (1985) |
| Andy Moeller | Offensive line | 7 | Michigan (1986) |
| Moe Ankney | Defensive coordinator | 6 | Bowling Green (1963) |
| Dave Toub | Defensive line | 2 | UTEP (1985) |
| Ricky Hunley | Linebackers & associate head coach | 6 | Arizona (1984) |
| Brian Stewart | defensive backs | 1 | Northern Arizona (1988) |