| Men's World Open 1999 | |
| Number: | 23 |
| Series: | PSA World Squash Championship |
| Type: | PSA |
| Location: |  Giza, Cairo, Egypt |
| Dates: | September 10–17, 1999 |
| Category: | PSA World Open |
| Prize Money: | $ 170,000 |
| Champion: | Peter Nicol |
| Runner-Up: | Ahmed Barada |
| Semi-Finalists: |  Jonathon PowerMartin Heath |
| Prev: | 1998  |
| Next: |  2002 |
The 1999 PSA Men's World Open Squash Championship is the men's edition of the 1999 World Open, which serves as the individual world championship for squash players. The event took place in Giza, Cairo in Egypt from 10 September to 17 September 1999. Peter Nicol won his first World Open title, defeating Ahmed Barada in the final.