The women's 4 x 400 metres relay event at the 1999 European Athletics U23 Championships was held in Göteborg, Sweden, at Ullevi on 31 July and 1 August 1999.
| Gold | Tatyana Levina Irina Yemelyanova Marina Grishakova Svetlana Pospelova  | |
| Silver | Nicole Marahrens Anika Ahrens Ulrike Urbansky Claudia Marx | |
| Bronze | Ramona Popovici Anca Safta Andrea Burlacu Otilia Ruicu  |
1 August
| Rank | Nation | Competitors | Time | Notes | ||
|---|---|---|---|---|---|---|
| align=left | | 3:29.04 | CR | |||
| align=left | 3:29.37 | |||||
| align=left | | 3:31.71 | ||||
| 4 | align=left |  | 3:33.28 | |||
| 5 | align=left |  | 3:33.56 | |||
| 6 | align=left |  | 3:33.59 | |||
| 7 | align=left |  | 3:35.73 | |||
| align=left |  | DNF |
31 July
Qualified: first 3 in each heat and 2 best to the Final
| Rank | Nation | Competitors | Time | Notes | ||
|---|---|---|---|---|---|---|
| 1 | align=left | | 3:32.39 | Q | ||
| 2 | align=left | | 3:33.49 | Q | ||
| 3 | align=left | | 3:34.65 | Q | ||
| 4 | align=left |  | 3:35.08 | |||
| 5 | align=left | 3:37.10 |
| Rank | Nation | Competitors | Time | Notes | ||
|---|---|---|---|---|---|---|
| 1 | align=left | | 3:30.87 | Q, CR | ||
| 2 | align=left | 3:31.65 | Q | |||
| 3 | align=left | | 3:31.70 | Q | ||
| 4 | align=left | | 3:31.80 | q | ||
| 5 | align=left | | 3:34.71 | q |
According to an unofficial count, 42 athletes from 10 countries participated in the event.
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