The men's 4 x 100 metres relay event at the 1999 European Athletics U23 Championships was held in Göteborg, Sweden, at Ullevi on 31 July and 1 August 1999.
| Gold | Christian Malcolm Jamie Henthorn John Stewart Mark Findlay  | |
| Silver | Jérôme Éyana Frédéric Krantz Cédric Gold Daig David Patros  | |
| Bronze | Alexander Kosenkow Stefan Holz Michael Schäfer Falk Schrader |
1 August
| Rank | Nation | Competitors | Time | Notes | ||
|---|---|---|---|---|---|---|
| align=left | | 38.96 | CR | |||
| align=left | | 39.14 | ||||
| align=left | 39.69 | |||||
| 4 | align=left |  | 39.73 | |||
| 5 | align=left |  | 39.78 | |||
| 6 | align=left |  | 39.80 | |||
| 7 | align=left |  | 39.93 | |||
| 8 | align=left | 39.98 |
31 July
Qualified: first 3 in each heat and 2 best to the Final
| Rank | Nation | Competitors | Time | Notes | ||
|---|---|---|---|---|---|---|
| 1 | align=left | | 39.76 | Q | ||
| 2 | align=left | | 39.90 | Q | ||
| 3 | align=left | | 39.92 | Q | ||
| 4 | align=left | 40.08 | q | |||
| 5 | align=left | 40.16 | ||||
| align=left |  | DNF |
| Rank | Nation | Competitors | Time | Notes | ||
|---|---|---|---|---|---|---|
| 1 | align=left | 39.17 | Q | |||
| 2 | align=left | | 39.58 | Q | ||
| 3 | align=left | 39.68 | Q | |||
| 4 | align=left | | 39.99 | q | ||
| align=left | DQ | |||||
| align=left |  | DNF |
According to an unofficial count, 51 athletes from 12 countries participated in the event.
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