| Election Name: | Durham mayoral election, 1999 |
| Type: | Presidential |
| Ongoing: | no |
| Previous Election: | 1997 Durham mayoral election |
| Previous Year: | 1997 |
| Next Election: | 2001 Durham mayoral election |
| Next Year: | 2001 |
| Election Date: | November 2, 1999 |
| Candidate1: | Nick Tennyson |
| Party1: | Nonpartisan candidate |
| Popular Vote1: | 17,119 |
| Percentage1: | 61.45% |
| Candidate2: | Floyd McKissick Jr. |
| Party2: | Nonpartisan candidate |
| Popular Vote2: | 10,572 |
| Percentage2: | 37.95% |
| Mayor | |
| Before Election: | Nick Tennyson |
| Before Party: | Republican Party (United States) |
| After Election: | Nick Tennyson |
| After Party: | Republican Party (United States) |
The 1999 Durham mayoral election was held on November 2, 1999 to elect the mayor of Durham, North Carolina. It saw the reelection of incumbent mayor Nick Tennyson.
The date of the primary was October 5, 1999.