| Champ: |  Natasha Zvereva |
| Runner: |  Nathalie Tauziat |
| Score: | 0–6, 7–5, 6–3 |
| Draw: | 28 |
| Seeds: | 8 |
| Type: | singles doubles |
See main article: 1999 Direct Line International Championships. The 1999 Direct Line International Championships singles was the singles event of the twenty-fifth edition of the Eastbourne International, a WTA Tier II tournament held in Eastbourne, England, United Kingdom and part of the European grass court season. Jana Novotná was the defending champion but did not participate this year, her final on tour before retiring in the fall.
Natasha Zvereva won in the final 0–6, 7–5, 6–3 against Nathalie Tauziat.
The top four seeds received a bye to the second round.
