| Tourney Name: | Copa Merconorte |
| Yearr: | 1999 |
| Dates: | 28 July – 22 December 1999 |
| Num Teams: | 12 |
| Associations: | 5 |
| Champion Other: |  América de Cali |
| Count: | 1 |
| Second Other: | Santa Fe |
| Matches: | 42 |
| Goals: | 122 |
| Top Scorer: |  Juan Enrique García (6) |
| Prevseason: | 1998 |
| Nextseason: | 2000 |
The 1999 Copa Merconorte was an association football tournament held in 1999. América de Cali of Colombia beat Santa Fe also of Colombia in the final.
| width=125 | Country | width=150 | Team |
|---|---|---|---|
(1 berth) | The Strongest | ||
(4 berths) | América de Cali | ||
| Atlético Nacional | |||
| Millonarios | |||
| Santa Fe | |||
(3 berths) | |||
| El Nacional | |||
(3 berths) | |||
| Sporting Cristal | |||
(1 berth) | Caracas | ||
Each team played the other teams in the group twice during the group stage. The first place team advanced to the second round.
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