| Sport: | football |
| Year: | 1999 |
| Team: | Canisius Golden Griffins |
| Conference: | Metro Atlantic Athletic Conference |
| Short Conf: | MAAC |
| Record: | 1–10 |
| Conf Record: | 0–8 |
| Hc Year: | 5th |
The 1999 Canisius Golden Griffins football team represented Canisius College in the 1999 NCAA Division I-AA football season. The Golden Griffins offense scored 133 points while the defense allowed 431 points.