The 1999 Advanta Championships of Philadelphia was a women's tennis tournament played on indoor hard courts in Philadelphia, United States. It was part of Tier II of the 1999 WTA Tour. It was the 17th edition of the tournament and was held from November 8 through November 14, 1999. Second-seeded Lindsay Davenport won the singles title and earned $80,000 first-prize money.
| Country | Player | Rank | Seed | |
|---|---|---|---|---|
| Martina Hingis | 1 | 1 | ||
 United States | Lindsay Davenport | 2 | 2 | |
| United States | Venus Williams | 3 | 3 | |
 France | Nathalie Tauziat | 7 | 4 | |
| France | Julie Halard-Decugis | 9 | 5 | |
| Amanda Coetzer | 10 | 6 | ||
 Belgium | Dominique Van Roost | 13 | 7 | |
 Russian Federation | Anna Kournikova | 12 | 8 |
The following players received wildcards into the singles main draw:
The following players received wildcards into the doubles main draw:
The following players received entry from the singles qualifying draw:
The following players received entry as lucky losers:
The following players received entry from the doubles qualifying draw:
See main article: 1999 Advanta Championships of Philadelphia – Singles. Lindsay Davenport defeated Martina Hingis, 6–3, 6–4
See main article: 1999 Advanta Championships of Philadelphia – Doubles. Lisa Raymond / 
Rennae Stubbs defeated Chanda Rubin / Sandrine Testud, 6–1, 7–6(7–2)
