The 1999 Acura Classic doubles was the doubles event of the twentieth edition of the third tournament in the US Open Series. Martina Hingis and Natasha Zvereva were the reigning champions but Hingis did not compete this year. Zvereva partnered Mary Pierce – they were defeated in the first round by Cara Black and Irina Selyutina.
Arantxa Sánchez Vicario and Larisa Neiland won the title, defeating third seeds Lisa Raymond and Rennae Stubbs in the final.
