| Club: | RCD Espanyol |
| Season: | 1999–2000 |
| Chrtitle: | President |
| Chairman: | Daniel Sánchez Llibre |
| Mgrtitle: | Head coach |
| Manager: | Miguel Ángel Brindisi (to 16 January) Paco Flores (from 19 January) |
| Stadium: | Estadi Olímpic de Montjuïc |
| League: | La Liga |
| League Result: | 14th |
| Cup1: | Copa del Rey |
| Cup1 Result: | Winners |
| Cup2: | UEFA Intertoto Cup |
| Cup2 Result: | Third round |
| League Topscorer: | Raúl Tamudo (10) |
| Season Topscorer: | Raúl Tamudo (11) |
| Prevseason: | 1998–99 |
| Nextseason: | 2000–01 |
The 1999–2000 season was the 65th season in the existence of RCD Espanyol and the club's sixth consecutive season in the top flight of Spanish football. In addition to the domestic league, Espanyol participated in this season's edition of the Copa del Rey, which they won, and UEFA Intertoto Cup.
Updated on 28 January 2023[1] [2] [3] [4] |-|colspan="12"|Players who have left the club after the start of the season: