| Competition: | Nemzeti Bajnokság I |
| Season: | 1999–2000 |
| Winners: | Dunaferr |
| Relegated: | Siófok Diósgyőr Vác Szeged LC |
| Continentalcup1: | Champions League |
| Continentalcup1 Qualifiers: | Dunaferr |
| Continentalcup2: | UEFA Cup |
| Continentalcup2 Qualifiers: | MTK Budapest Vasas |
| Continentalcup3: | Intertoto Cup |
| Continentalcup3 Qualifiers: | Tatabánya |
| League Topscorer: | Attila Tököli (22) |
| Biggest Home Win: | Ferencváros 8–0 Vác |
| Biggest Away Win: | Vác 0–5 MTK Vác 0–5 Debrecen |
| Highest Scoring: | Ferencváros 8–0 Vác |
| Matches: | 289 |
| Total Goals: | 721 |
| Prevseason: | 1998–99 |
| Nextseason: | 2000–01 |
The 1999–2000 Nemzeti Bajnokság I, also known as NB I, was the 98th season of top-tier football in Hungary. The league was officially named Professzionális Nemzeti Bajnokság (PNB) for sponsorship reasons. The season started on 7 August 1999 and ended on 27 May 2000.
It was contested by 18 teams, and Dunaferr FC won the championship.
| Rank | Scorer | Club | Goals |
|---|---|---|---|
| 1 |  Attila Tököli | Dunaferr SE | 22 |
| 2 | Péter Horváth | Ferencvárosi TC | 19 |
| 3 | Mihály Tóth | Ferencvárosi TC | 18 |
| 4 | Gábor Zavadszky | Dunaferr SE | 14 |
| 5 | Béla Illés | MTK Hungária | 13 |
| Péter Kabát | Vasas SC | 13 | |
| Krisztián Kenesei | MTK Hungária | 13 | |
| 8 | Gyula Horváth | Nagykanizsai Olajbányász | 11 |
| Zoltán Kovács | Újpest FC | 11 | |
| Norbert Tóth | Újpest FC | 11 | |