| Sport: | basketball |
| Year: | 1999–2000 |
| Team: | Missouri Tigers |
| Conference: | Big 12 Conference |
| Short Conf: | Big 12 |
| Record: | 18–13 |
| Conf Record: | 10–6 |
| Head Coach: | Quinn Snyder |
| Hc Year: | 1st |
| Asst Coach1: | Igor Kokoškov |
| Ac1 Year: | 1st |
| Asst Coach2: | Tony Harvey |
| Ac2 Year: | 1st |
| Arena: | Hearnes Center |
| Tourney: | NCAA tournament |
| Tourney Result: | First round |
The 1999–2000 Missouri Tigers men's basketball team represented the University of Missouri during the 1999–2000 NCAA men's college basketball season.