| Mode: | Basketball |
| Year: | 1999–2000 |
| Team: | Louisville Cardinals |
| Conference: | Conference USA |
| Short Conf: | CUSA |
| Record: | 19–12 |
| Conf Record: | 10–6 |
| Hc Year: | 29th |
| Tourney Result: | Round of 32 |
The 1999–2000 Louisville Cardinals men's basketball team represented the University of Louisville in the 1999 - 2000 NCAA Division I men's basketball season. The head coach was Denny Crum[1] and the team finished the season with an overall record of 19–12.[2]