| Season: | 1999–00 |
| Relegated: | Cefire Burela, Sol Fuerza Salamanca & Fórum Filatélico R. Baixas |
| League Topscorer: | Joan, 68 goals |
| Biggest Home Win: | Airtel Boomerang 13–0 O'Parrulo Indunor |
| Biggest Away Win: | Mínguez Sáez Cartagena 3–10 Playas de Castellón |
| Highest Scoring: | Playas de Castellón 15–4 Miró Martorell |
| Matches: | 306 |
| Total Goals: | 2468 |
| Nextseason: | 2000–01 |
The 1999–00 season of the División de Honor de Futsal is the 11th season of top-tier futsal in Spain.
| Title Play-Off | ||
| Relegation |
| P | Team | Pld | W | D | L | GF | GA | Pts | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Playas de Castellón | 34 | 30 | 2 | 2 | 204 | 88 | 92 | |
| 2 | Caja Segovia | 34 | 24 | 6 | 4 | 156 | 102 | 78 | |
| 3 | CLM Talavera | 34 | 24 | 5 | 5 | 174 | 110 | 77 | |
| 4 | ElPozo Murcia | 34 | 23 | 4 | 7 | 147 | 110 | 73 | |
| 5 | Airtel Boomerang | 34 | 21 | 8 | 5 | 168 | 95 | 71 | |
| 6 | O Parrulo Indunor | 34 | 19 | 3 | 12 | 134 | 137 | 60 | |
| 7 | Ourense | 34 | 17 | 4 | 13 | 148 | 138 | 55 | |
| 8 | C. DRY Fiat Torrejón | 34 | 15 | 4 | 15 | 147 | 152 | 49 | |
| 9 | Mínguez Sáez Cartagena | 34 | 12 | 7 | 15 | 122 | 135 | 43 | |
| 10 | MRA Ingeteam Xota | 34 | 13 | 2 | 19 | 144 | 157 | 41 | |
| 11 | Industrias García | 34 | 13 | 1 | 20 | 150 | 158 | 40 | |
| 12 | Foticos Zaragoza | 34 | 13 | 1 | 20 | 130 | 148 | 40 | |
| 13 | Dulma Astorga | 34 | 11 | 4 | 19 | 109 | 141 | 37 | |
| 14 | Miró Martorell | 34 | 11 | 3 | 20 | 126 | 159 | 36 | |
| 15 | Caja San Fernando Jerez | 34 | 9 | 6 | 19 | 108 | 148 | 33 | |
| 16 | Fórum Filatélico R. Baixas | 34 | 6 | 3 | 25 | 103 | 159 | 21 | |
| 17 | Sol Fuerza Salamanca | 34 | 7 | 0 | 27 | 87 | 141 | 21 | |
| 18 | Cefire Burela | 34 | 6 | 1 | 27 | 107 | 186 | 19 |
| Player | Goals | Team | |
|---|---|---|---|
| Joan | 68 | CLM Talavera | |
| Edesio | 66 | Playas de Castellón | |
| Paulo Roberto | 66 | ElPozo Murcia | |
| Andreu | 49 | CLM Talavera | |
| Vinicius | 48 | Airtel Boomerang | |
| Daniel | 47 | Caja Segovia | |
| Afranio | 44 | MRA Ingeteam Xota | |
| Javi Rodríguez | 41 | Playas de Castellón | |
| Cupim | 40 | Playas de Castellón | |
| Kel | 39 | Dulma Astorga |