| Mode: | Basketball |
| Year: | 1999–2000 |
| Team: | Creighton Bluejays |
| Conference: | Missouri Valley Conference |
| Short Conf: | MVC |
| Record: | 23–10 |
| Conf Record: | 11–7 |
| Head Coach: | Dana Altman (6th year) |
| Asst Coach1: | Greg Grensing (6th year) |
| Asst Coach2: | Len Gordy (6th year) |
| Asst Coach3: | Darian DeVries (2nd year) |
| Champion: | MVC tournament champion |
| Bowl Result: | first round |
The 1999–2000 Creighton Bluejays men's basketball team represented Creighton University during the 1999–2000 NCAA Division I men's basketball season. The Bluejays, led by head coach Dana Altman, played their home games at the Omaha Civic Auditorium. The Jays finished with a 23-10 record, and won the Missouri Valley Conference tournament to earn an automatic bid to the 2001 NCAA tournament.
|-!colspan=9 style=| Regular season|-!colspan=9 style=| Missouri Valley Conference tournament|-!colspan=9 style=| 2000 NCAA tournament