| Competition: | Venezuelan Primera División |
| Season: | 1999–2000 |
| Winners: | Deportivo Táchira (5th title) |
| Prevseason: | 1998–99 |
| Nextseason: | 2000–01 |
The 1999–2000 season of the Venezuelan Primera División, the top category of Venezuelan football, was played by 12 teams. The national champions were Deportivo Táchira.