Amanda Coetzer defeated Irina Spîrlea in the final, 6–3, 6–4 to win the singles tennis title at the 1998 Family Circle Cup.
Martina Hingis was the reigning champion, but did not compete that year.
A champion seed is indicated in bold text while text in italics indicates the round in which that seed was eliminated. The top eight seeds received a bye to the second round.