| Season: | 1998–99 |
| Winners: | Dynamo Kyiv 7th title |
| League Topscorer: | (18) Andriy Shevchenko (Dynamo) |
| Biggest Home Win: | Dynamo - Prykarpattia 7:0 Shakhtar - Mykolaiv 7:0 |
| Biggest Away Win: | Metalist - Dynamo 1:6 Zirka - Dynamo 0:5 |
| Highest Scoring: | Shakhtar - Vorskla 7:3 |
| Matches: | 240 |
| Nextseason: | 1999–2000 |
The 1998–99 Vyshcha Liha season was the 8th since its establishment. FC Dynamo Kyiv were the defending champions.
Notes: Games between Dynamo Kyiv and CSKA Kyiv were played at Republican Stadium.
| Team | Outgoing head coach | Manner of departure | Date of vacancy | Table | Incoming head coach | Date of appointment | Table | |
|---|---|---|---|---|---|---|---|---|
| FC Nyva Ternopil |  Leonid Ishchuk | pre-season | Ihor Yurchenko | pre-season | ||||
| FC CSKA Kyiv | Serhiy Morozov | pre-season | Volodymyr Bezsonov | pre-season |
| Rank | Player | Club | Goals (Pen.) |
|---|---|---|---|
| 1 | Andriy Shevchenko | Dynamo Kyiv | 18 (1) |
| 2 | Ivan Hetsko | Karpaty Lviv | 16 |
| Oleksandr Palyanytsia | Karpaty Lviv | 16 (5) | |
| 4 | Valentyn Poltavets | Metalurh Zaporizhzhya | 13 (3) |
| 5 | Andriy Vorobei | Shakhtar Donetsk | 11 |
| 6 | Oleksiy Osipov | Tavriya Simferopol | 11 (3) |
| 7 |  Alexander Khatskevich | Dynamo Kyiv | 10 |
| 8 | Oleksandr Haidash | Tavriya Simferopol | 9 |
 Avtandil Kapanadze | Nyva Ternopil | 9 | |
| Ihor Kislov | Zirka Kirovohrad | 9 | |
| Ihor Kostiuk | Vorskla Poltava | 9 | |
| Vitaliy Pantilov | Metalurh Mariupol | 9 | |
| Serhii Rebrov | Dynamo Kyiv | 9 | |
| Yuriy Selezniov | Shakhtar Donetsk | 9 |