| Champ: |  Conchita Martínez |
| Runner: | Magdalena Maleeva |
| Score: | 6–1, 6–1 |
| Draw: | 56 |
| Seeds: | 16 |
| Type: | singles doubles |
Defending champion Conchita Martínez defeated Magdalena Maleeva in the final, 6–1, 6–1 to win the singles tennis title at the 1995 Family Circle Cup.
A champion seed is indicated in bold text while text in italics indicates the round in which that seed was eliminated. The top eight seeds received a bye to the second round.
Arantxa Sánchez Vicario (quarterfinals) Conchita Martínez (champion)
Gabriela Sabatini (second round)
Natasha Zvereva (semifinals)
Lori McNeil (second round)
Judith Wiesner (second round) Inés Gorrochategui (first round) Zina Garrison-Jackson (first round) Lisa Raymond (second round)
Sabine Appelmans (first round)
Sandra Cecchini (first round)