| Mode: | football |
| Year: | 1995 |
| Team: | Cal Poly Mustangs |
| Conference: | American West Conference |
| Short Conf: | AWC |
| Record: | 5–6 |
| Conf Record: | 2–1 |
| Head Coach: | Andre Patterson |
| Hc Year: | 2nd |
| Stadium: | Mustang Stadium |
The 1995 Cal Poly Mustangs football team represented California Polytechnic State University[1] during the 1995 NCAA Division I-AA football season.
Cal Poly competed in the last year of the American West Conference (AWC). They would compete as a Division I-AA Independent starting in 1996. The 1995 Mustangs were led by second-year head coach Andre Patterson and played home games at Mustang Stadium in San Luis Obispo, California. They finished the season with a record of five wins and six losses (5–6, 2–1 AWC). Overall, the team outscored its opponents 411–271 for the season.