| Election Name: | 1994 United States Senate election in Missouri |
| Country: | Missouri |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1988 United States Senate election in Missouri |
| Previous Year: | 1988 |
| Next Election: | 2000 United States Senate election in Missouri |
| Next Year: | 2000 |
| Election Date: | November 8, 1994 |
| Image1: | Senator John Ashcroft1.jpg |
| Nominee1: | John Ashcroft |
| Party1: | Republican Party (United States) |
| Popular Vote1: | 1,060,149 |
| Percentage1: | 59.72% |
| Nominee2: | Alan Wheat |
| Party2: | Democratic Party (United States) |
| Popular Vote2: | 633,697 |
| Percentage2: | 35.70% |
| Map Size: | 275px |
| U.S. Senator | |
| Before Election: | John Danforth |
| Before Party: | Republican Party (United States) |
| After Election: | John Ashcroft |
| After Party: | Republican Party (United States) |
The 1994 United States Senate election in Missouri was held November 8, 1994. Incumbent Republican U.S. Senator John Danforth decided to retire and not seek re-election. Former Governor of Missouri John Ashcroft won the open seat in a landslide.[1]